default SYNTHESIS OF NEW DERIVATIVES OF SATURATED -LACTONES COMPRISING 5-OXOTETRAHYDROFURAN, AROMATIC, SULFAMOYL AND HETEROAROMATIC FRAGMENTS

Владелец Число скачиваний: 70

УДК 547.724

Karapetyan Lusine V., Tokmajyan Gayane G.

Yerevan State University

(Yerevan, Armenia)

Abstract. Potent biological active new compounds comprising 5oxotetrahydrofuran, aromatic, sulfamoyl, and heteroaromatic fragments were synthesized according to two strategies from 2-(2,2-dimethyl-5- oxotetrahydrofuran3-yl)acetyl chloride and analgesic and sulfanilamide drugs. The methodologies are simple, rapid, and inexpensive affording high yields of the products with operational simplicity.

Keywords: isothiocyanate; 5-oxotetrahydrofuran, potassium thiocyanate; analgesic and sulfanilamide drugs.